Pediatric Rheumatology

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Open Access Case Report

An adolescent with both Wegener's Granulomatosis and chronic blastomycosis

Reem Abdwani1*, Kristin Houghton2, Simon Dobson3, Maureen O' Sullivan4 and Peter Malleson2

Author Affiliations

1 Division of Child health, Sultan Qaboos University Hospital, Muscat, Oman

2 Division of Pediatric Rheumatology, University of British Columbia, Vancouver, Canada

3 Division of Infectious Disease, University of British Columbia, Vancouver, Canada

4 Department of Pathology & Laboratory Medicine, University of British Columbia, Vancouver, Canada

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Pediatric Rheumatology 2008, 6:13 doi:10.1186/1546-0096-6-13

Published: 3 August 2008

Abstract

We report a case of Wegener's Granulomatosis (WG) associated with blastomycosis. This appears to be the first case report of WG co-existing with a tissue proven blastomycosis infection. The temporal correlation of the two conditions suggests that blastomycosis infection (and therefore possibly other fungal infections), may trigger the systemic granulomatous vasculitis in a predisposed individual; a provocative supposition warranting further study.