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Delphi 2 Responses in order of descending number of votes |
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| PROBLEM |
TREATMENT |
VOTES |
|
|
||
| Systemic onset juvenile rheumatoid arthritis |
Anti-IL-6 receptor antibody |
62 |
| Uveitis (juvenile rheumatoid arthritis, sarcoid, or idiopathic) unresponsive to methotrexate |
Infliximab |
50 |
| Pediatric systemic lupus erythematosus |
Mycophenolate mofetil |
48 |
| Thrombocytopenia unresponsive to standard therapy in systemic lupus erythematosus |
Rituximab |
47 |
| Juvenile dermatomyositis unresponsive to prednisone and disease-modifying anti-rheumatic drugs |
Enbrel |
43 |
| Systemic onset juvenile rheumatoid arthritis |
Thalidomide |
43 |
| Systemic onset juvenile rheumatoid arthritis |
Anakinra |
36 |
| Localized scleroderma |
Combination: steroids and methotrexate |
35 |
| Juvenile dermatomyositis unresponsive to prednisone and disease-modifying anti-rheumatic drugs |
Infliximab |
29 |
| Rash of juvenile dermatomyositis |
Topical tacrolimus |
27 |
| Systemic lupus erythematosus proliferative nephritis unresponsive to pulse cyclophosphamide and mycophenolate mofetil |
Combination: pulse cyclophosphamide and mycophenolate mofetil |
25 |
| Chronic Recurrent Multifocal Osteomyelitis that is not controlled by non-steroid anti-inflammatory drugs and/or that requires corticosteroids |
Bisphosphonates |
24 |
| Localized scleroderma |
Methotrexate orally |
20 |
| Linear scleroderma refractory to oral or subcutaneous methotrexate treatment |
Oral mycophenolate mofetil treatment |
19 |
| Henoch Scholein Purpura |
Glucocorticoid treatment |
18 |
| Osteoporosis |
Alendronate and other possibilities |
18 |
| Pauciarticular juvenile rheumatoid arthritis |
Intraarticular steroids |
17 |
| Systemic onset juvenile rheumatoid arthritis |
Combination:TNF blockers and thalidomide |
17 |
| Behcet's |
Infliximab |
16 |
| Early polyarticular juvenile rheumatoid arthritis |
CTLA4-1g |
16 |
| Macrophage activation syndrome |
Combination: cyclosporin + corticosteroids |
15 |
| Sarcoid arthritis |
Enbrel |
15 |
| Severe systemic lupus erythematosus – cyclophosphamide dependent or resistant |
Intravenous fludarabine |
15 |
| Rash of systemic lupus erythematosus |
Topical tacrolimus |
14 |
| Acute rheumatic fever |
Naproxen |
13 |
| Henoch Scholein Purpura with abdominal pain |
Glucocorticoid treatment |
13 |
| Juvenile rheumatoid arthritis-temporomandibular joint arthritis |
Corticosteroid joint injections |
13 |
| Systemic onset juvenile rheumatoid arthritis |
Oral intravenous immunoglobulin as adjuvant therapy |
10 |
| Familial Mediterranean fever not responsive to colchicine |
Anakinra |
8 |
| Refractory iritis in juvenile rheumatoid arthritis |
Cyclosporin |
8 |
| Osteoporosis |
Vitamin D – the various preparations |
7 |
| Raynaud's 10 and 20 |
Biofeedback |
7 |
| Familial Mediterranean fever |
Anti-Interleukin 1 |
5 |
| Systemic onset juvenile rheumatoid arthritis |
Combination: hydroxychloroquine and standard therapy |
2 |
| Systemic onset juvenile rheumatoid arthritis |
Combination: thalidomide and cyclosporin |
2 |
Ota et al. Pediatric Rheumatology 2008 6:5 doi:10.1186/1546-0096-6-5 |
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