Analysis of the classical, alternative, and MBL pathways of the complement system in juvenile idiopathic arthritis

doi:10.1186/1546-0096-6-S1-P1

Pediatric Rheumatology

Volume 6
Suppl 1

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Scheiring J
Petzelsberger B
Prelog M
Zimmerhackl LB

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Scheiring J
Petzelsberger B
Prelog M
Zimmerhackl LB
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This article is part of the supplement: 15th Paediatric Rheumatology European Society (PreS) Congress .

Poster presentation

Analysis of the classical, alternative, and MBL pathways of the complement system in juvenile idiopathic arthritis

J Brunner, J Scheiring, B Petzelsberger, M Prelog and L-B Zimmerhackl

Department of Pediatrics, Innsbruck Medical University, Innsbruck, Austria

corresponding author email

from 15^thPaediatric Rheumatology European Society (PreS) Congress
London, UK. 14–17 September 2008

Pediatric Rheumatology 2008, 6(Suppl 1):P1doi:10.1186/1546-0096-6-S1-P1


Published:	15 September 2008

First paragraph (this article has no abstract)

The complement system is involved in the host defence by recognition and elimination of potentially harmful exogenous and endogenous structures from the human body. Activation of complement may also promote inflammatory reactions and cause tissue damage if adequate control is not provided by the complement regulatory proteins. Significant amounts of biologically active products arising from complement activation have been detected in patients with rheumatoid arthritis.