Pediatric Rheumatology

unofficial impact factor 1.74

This article is part of the supplement: 15th Paediatric Rheumatology European Society (PreS) Congress

Open Access Poster presentation

The TRAF1/C5 region is a risk factor for polyarthritis in juvenile idiopathic arthritis

HM Albers1*, FAS Kurreeman1, JJ Houwing-Duistermaat1, DMC Brinkman1, SSM Kamphuis2, HJ Girschick3, C Wouters4, MAJ van Rossum5, W Verduyn1, REM Toes1, TWJ Huizinga1, MW Schilham1 and R ten Cate1

  • * Corresponding author: HM Albers

Author Affiliations

1 Leiden University Medical Center, Leiden, Netherlands

2 Erasmus Medical Center – Sophia Children's Hospital, Rotterdam, Netherlands

3 University of Wuerzburg, Wuerzburg, Germany

4 University Hospital Gasthuisberg, Leuven, Belgium

5 Emma Children's Hospital AMC, Amsterdam, Netherlands

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Pediatric Rheumatology 2008, 6(Suppl 1):P11 doi:10.1186/1546-0096-6-S1-P11

Published: 15 September 2008

First paragraph (this article has no abstract)

Juvenile idiopathic arthritis (JIA) is a chronic disorder in which both genetic and environmental factors are involved. Recently we identified the TRAF1/C5 region (located on chromosome 9q33-34) as a risk factor for rheumatoid arthritis (RA) (pcombined = 1.4 × 10-8) [1]. In the present study the association of the TRAF1/C5 region with the susceptibility to JIA was investigated.