The TRAF1/C5 region is a risk factor for polyarthritis in juvenile idiopathic arthritis

doi:10.1186/1546-0096-6-S1-P11

Pediatric Rheumatology

Volume 6
Suppl 1

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Albers HM
Kurreeman FAS
Houwing-Duistermaat JJ
Brinkman DMC
Kamphuis SSM
Girschick HJ
Wouters C
van Rossum MAJ
Verduyn W
Toes REM
Huizinga TWJ
Schilham MW
ten Cate R

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Albers HM
Kurreeman FAS
Houwing-Duistermaat JJ
Brinkman DMC
Kamphuis SSM
Girschick HJ
Wouters C
van Rossum MAJ
Verduyn W
Toes REM
Huizinga TWJ
Schilham MW
ten Cate R
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This article is part of the supplement: 15th Paediatric Rheumatology European Society (PreS) Congress .

Poster presentation

The TRAF1/C5 region is a risk factor for polyarthritis in juvenile idiopathic arthritis

HM Albers¹, FAS Kurreeman¹, JJ Houwing-Duistermaat¹, DMC Brinkman¹, SSM Kamphuis², HJ Girschick³, C Wouters⁴, MAJ van Rossum⁵, W Verduyn¹, REM Toes¹, TWJ Huizinga¹, MW Schilham¹ and R ten Cate¹

¹Leiden University Medical Center, Leiden, Netherlands

²Erasmus Medical Center – Sophia Children's Hospital, Rotterdam, Netherlands

³University of Wuerzburg, Wuerzburg, Germany

⁴University Hospital Gasthuisberg, Leuven, Belgium

⁵Emma Children's Hospital AMC, Amsterdam, Netherlands

corresponding author email

from 15^thPaediatric Rheumatology European Society (PreS) Congress
London, UK. 14–17 September 2008

Pediatric Rheumatology 2008, 6(Suppl 1):P11doi:10.1186/1546-0096-6-S1-P11


Published:	15 September 2008

First paragraph (this article has no abstract)

Juvenile idiopathic arthritis (JIA) is a chronic disorder in which both genetic and environmental factors are involved. Recently we identified the TRAF1/C5 region (located on chromosome 9q33-34) as a risk factor for rheumatoid arthritis (RA) (p_combined= 1.4 × 10^-8) [1]. In the present study the association of the TRAF1/C5 region with the susceptibility to JIA was investigated.