Pediatric Rheumatology

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This article is part of the supplement: 15th Paediatric Rheumatology European Society (PreS) Congress

Open Access Poster presentation

FOXP3 expression in peripheral blood and synovial cells of patients with juvenile idiopathic arthritis: relationship with IL-17 at cytokine and molecular level

B Olivito*, S Ciullini, M Moriondo, L Betti, E Gambineri, G Simonini, C Azzari, M De Martino and R Cimaz

  • * Corresponding author: B Olivito

Author Affiliations

A. Meyer University Children's Hospital, Florence, Italy

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Pediatric Rheumatology 2008, 6(Suppl 1):P13 doi:10.1186/1546-0096-6-S1-P13

Published: 15 September 2008

First paragraph (this article has no abstract)

Recently, CD4+CD25+ FOXP3+ (Treg) cells have emerged as master regulator of immune responses, and their role as well as that of IL-17 producing lymphocytes (Th17), is under study in the pathogenesis of juvenile idiopathic arthritis (JIA).