Pediatric Rheumatology

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This article is part of the supplement: 15th Paediatric Rheumatology European Society (PreS) Congress

Open Access Poster presentation

Association between IL2RA and juvenile idiopathic arthritis (JIA) disease severity at first presentation to paediatric rheumatology: results from the Childhood Arthritis Prospective Study (CAPS)

KL Hyrich1*, SD Lal1, A Hinks1, LR Wedderburn2, J Gardner-Medwin3, H Foster5, A Chieng6, J Davidson3, E Baildam4 and W Thomson1

  • * Corresponding author: KL Hyrich

Author Affiliations

1 University of Manchester, Manchester, UK

2 Institute of Child Health, London, UK

3 Royal Hospital for Sick Children, Glasgow, UK

4 Royal Liverpool Children's Hospital, Liverpool, UK

5 University of Newcastle, Newcastle, UK

6 Royal Manchester Children's Hospital, Manchester, UK

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Pediatric Rheumatology 2008, 6(Suppl 1):P14 doi:10.1186/1546-0096-6-S1-P14

Published: 15 September 2008

First paragraph (this article has no abstract)

CAPS was designed to study clinical and genetic predictors of JIA outcome. The gene IL2RA has recently emerged as a JIA susceptibility locus. This study investigates the association between SNPs located within the IL2RA region and disease severity at first presentation to rheumatology.