This article is part of the supplement: 15th Paediatric Rheumatology European Society (PreS) Congress . Poster presentationMay antihistone antibodies replace antinuclear antibodies (ANA) as a predictor of uveitis in Juvenile idiopathic arthritis?1 Department of Pediatrics, University Hospital of North Norway and Institute of Community Medicine, University of Tromsø, Tromsø, Norway 2 Department of Pediatrics, University Hospital of North Norway, Tromsø, Norway 3 Institute of Community Medicine, University of Tromsø, Tromsø, Norway 4 Department of Women's and Children's Health, Uppsala University Children's Hospital, Uppsala, Sweden 5 Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology and Department of Pediatrics, St. Olavs Hospital, Trondheim, Norway
from 15th Paediatric Rheumatology European Society (PreS) Congress Pediatric Rheumatology 2008, 6(Suppl 1):P4doi:10.1186/1546-0096-6-S1-P4
First paragraph (this article has no abstract)Antihistone antibodies (AHA) are an ANA subtype reported to be associated with uveitis in Juvenile idiopathic arthritis (JIA). Enzyme-linked immunoassays (E-ANA) are increasingly used as a more standardized alternative to the immunofluorescense method on Hep-2 cells (IF-ANA). E-ANA, however, show no association with uveitis and should not be used in the diagnostic work-up of JIA. |
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