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This article is part of the supplement: 15th Paediatric Rheumatology European Society (PreS) Congress

Open Access Poster presentation

May antihistone antibodies replace antinuclear antibodies (ANA) as a predictor of uveitis in Juvenile idiopathic arthritis?

EB Nordal1*, NT Songstad2, B Straume3, L Berntson4 and M Rygg5

  • * Corresponding author: EB Nordal

Author Affiliations

1 Department of Pediatrics, University Hospital of North Norway and Institute of Community Medicine, University of Tromsø, Tromsø, Norway

2 Department of Pediatrics, University Hospital of North Norway, Tromsø, Norway

3 Institute of Community Medicine, University of Tromsø, Tromsø, Norway

4 Department of Women's and Children's Health, Uppsala University Children's Hospital, Uppsala, Sweden

5 Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology and Department of Pediatrics, St. Olavs Hospital, Trondheim, Norway

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Pediatric Rheumatology 2008, 6(Suppl 1):P4 doi:10.1186/1546-0096-6-S1-P4

Published: 15 September 2008

First paragraph (this article has no abstract)

Antihistone antibodies (AHA) are an ANA subtype reported to be associated with uveitis in Juvenile idiopathic arthritis (JIA). Enzyme-linked immunoassays (E-ANA) are increasingly used as a more standardized alternative to the immunofluorescense method on Hep-2 cells (IF-ANA). E-ANA, however, show no association with uveitis and should not be used in the diagnostic work-up of JIA.