Pediatric Rheumatology

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This article is part of the supplement: 15th Paediatric Rheumatology European Society (PreS) Congress

Open Access Poster presentation

Role of Vγ9Vδ2+ γδ T cells in juvenile idiopathic arthritis

M Gerstein1*, A Bendersky2, S Padeh1, I Bank2 and Y Berkun1

  • * Corresponding author: M Gerstein

Author Affiliations

1 Safra Children's Hospital at SHEBA Medical Center, Tel Aviv, Israel

2 Laboratory for Immunoregulation, Tel Aviv, Israel

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Pediatric Rheumatology 2008, 6(Suppl 1):P8 doi:10.1186/1546-0096-6-S1-P8

Published: 15 September 2008

First paragraph (this article has no abstract)

T cells (TC) bearing Vγ9Vδ2+ γδ TC receptor (TCR), are a subset of innate CD4-CD8- TC pro-inflammatory and immunoregulatory TC recognizing non-peptidic phosphorylated mediator isopentenyl pyrophosphate (IPP) in the mevalonate pathway. The role Vγ9Vδ2+ TC has never been explored in JIA joints.