Role of Vγ9Vδ2+ γδ T cells in juvenile idiopathic arthritis

doi:10.1186/1546-0096-6-S1-P8

Pediatric Rheumatology

Volume 6
Suppl 1

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This article is part of the supplement: 15th Paediatric Rheumatology European Society (PreS) Congress .

Poster presentation

Role of Vγ9Vδ2+ γδ T cells in juvenile idiopathic arthritis

M Gerstein¹, A Bendersky², S Padeh¹, I Bank² and Y Berkun¹

¹Safra Children's Hospital at SHEBA Medical Center, Tel Aviv, Israel

²Laboratory for Immunoregulation, Tel Aviv, Israel

corresponding author email

from 15^thPaediatric Rheumatology European Society (PreS) Congress
London, UK. 14–17 September 2008

Pediatric Rheumatology 2008, 6(Suppl 1):P8doi:10.1186/1546-0096-6-S1-P8


Published:	15 September 2008

First paragraph (this article has no abstract)

T cells (TC) bearing Vγ9Vδ2+ γδ TC receptor (TCR), are a subset of innate CD4-CD8- TC pro-inflammatory and immunoregulatory TC recognizing non-peptidic phosphorylated mediator isopentenyl pyrophosphate (IPP) in the mevalonate pathway. The role Vγ9Vδ2+ TC has never been explored in JIA joints.