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Infliximab for the treatment of intravenous immunoglobulin resistant Kawasaki disease complicated by coronary artery aneurysms: a case report

Robert J Brogan1 email, Despina Eleftheriou1 email, James Gnanapragasam2 email, Nigel J Klein3 email and Paul A Brogan1 email

Department of Paediatric Rheumatology, UCL Institute of Child Health and Great Ormond Street Hospital, 30 Guilford Street, London, UK

Congenital Cardiac Centre, North Wing, Southampton University Hospitals NHS Trust, Tremona Road, Southampton, UK

Department of Infectious disease and Microbiology, UCL Institute of Child Health and Great Ormond Street Hospital, 30 Guilford Street, London, UK

author email corresponding author email

Pediatric Rheumatology 2009, 7:3doi:10.1186/1546-0096-7-3

Published: 21 January 2009

Abstract

This case report describes an 8 year old boy with IVIG resistant Kawasaki disease complicated by severe bilateral coronary artery aneurysms successfully treated with infliximab, a monoclonal antibody against tumour necrosis factor alpha.


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