Pediatric Rheumatology

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Infliximab for the treatment of intravenous immunoglobulin resistant Kawasaki disease complicated by coronary artery aneurysms: a case report

Robert J Brogan1*, Despina Eleftheriou1, James Gnanapragasam2, Nigel J Klein3 and Paul A Brogan1

Author Affiliations

1 Department of Paediatric Rheumatology, UCL Institute of Child Health and Great Ormond Street Hospital, 30 Guilford Street, London, UK

2 Congenital Cardiac Centre, North Wing, Southampton University Hospitals NHS Trust, Tremona Road, Southampton, UK

3 Department of Infectious disease and Microbiology, UCL Institute of Child Health and Great Ormond Street Hospital, 30 Guilford Street, London, UK

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Pediatric Rheumatology 2009, 7:3 doi:10.1186/1546-0096-7-3

Published: 21 January 2009

Abstract

This case report describes an 8 year old boy with IVIG resistant Kawasaki disease complicated by severe bilateral coronary artery aneurysms successfully treated with infliximab, a monoclonal antibody against tumour necrosis factor alpha.